IVEX Lab - Advancing your research

In vivo imaging services using IVIS Lumina

Oncology studies

The IVIS Lumina II from Caliper Life Sciences provides a sensitive non-invasive real-time in vivo imaging system that enables to detect bioluminescent cancer cell lines and near-IR fluorescent imaging agents.

Using IVIS Lumina you can study:

  • Tumor development;
  • Metastasis;
  • Drug efficacy;
  • Vascularity;
  • Metabolic activity;
  • Hypoxia;
  • Cell death;
  • Inflammation;
  • Tumor-specific biomarkers

 Benefits in comparison to standard techniques (calipers):

  • Greater sensitivity;
  • Linearity of growth;
  • Earler detection;
  • Lower cost
 

Biodistribution

Non-invasive near-infrared (NIR) fluorescence allows detection and visualization of whole body tissue biodistribution of drug in real-time. IVIS Imaging System allows the tracking of multiple agents simultaneously by labeling targets with different fluorophores that emit different wavelengths.

  • Organ distribution;
  • Kinetics of penetration into tissue;
  • Routes of clearance and metabolism

Benefits:

  • Non-invasive;
  • Reduced cost;
  • Rapid biodistribution screening;
  • Robust;
  • Sensitive